Periodontal disease is a serious infection caused by bacteria under the gums. It is the #1 cause of tooth loos in adults in the US. However, many people decide to avoid treating gum disease in its early stages, and wait until it’s too late.

But you have a choice. Do more now, or risk further disease progression. If left untreated, gum disease can become advanced requiring painful and expensive surgery. In combination with scaling and root planing (SRP), we can apply ARESTIN® (minocycline HCl) Microspheres, 1 mg to help treat your gum disease.

It’s placed directly in the infected areas—or “pockets”—in your gums, where brushing and flossing can’t reach.


ARESTIN® starts working quickly, right at the source of infection, and keeps fighting bacteria long after you leave the dental office. 1,2

ARESTIN® fights infection and inflammation for 30 days,2 and provides significantly better results than scaling and root planing alone for up to 90 days.3

1. Oringer RJ, Al-Shammari KF, Aldredge WA, et al. Effect of locally administered minocycline microspheres on markers of bone resorption. J Periodontol 2002;73:835-842.
2. Goodson JM, Gunsollwy JC, Grossi SG, et al. Minocycline HCl microspheres reduce red-complex bacteria in periodontal disease therapy. J Periodontol 2007;78(8):1568-1579.
3. Williams RC, Paquette DW, Offenbacher S, et al. Treatment of periodontitis by local administration of minocycline microspheres: a controlled trial. J Periodontol 2001;72:1535-1544.


ATRIDOX®  is a medicated gel that contains an antibiotic called Doxycycline-hyclate. It  is placed at infected periodontal pockets.

How does ATRIDOX® work? Like Arestin®, ATRIDOX® gradually releases antibiotic medication to treat ongoing disease. Once in the pocket, the gel solidifies into a waxy substance. This allows it to remain in the region and gradually release medication for up to three weeks after placement.antidox

It kills bacteria associated with periodontal diease to stop the disease’s progression. Pairing antibiotic treatment with SRP has shown the most thorough results.